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Questão de Farmácia — Farmacologia — IDCAP 2024

FarmáciaFarmacologia
Código
qg223659
Banca
IDCAP
Órgão
HEG
Ano
2024
Nível
Superior
Cargo
Programa de Residência Multiprofissional em Cancerologia - Farmácia
Nausea and vomiting can be manifestations of a wide variety of conditions. Regarding 5-HT3 serotonin receptor antagonists, it is correct to say:
  1. AThey have a potent antiemetic effect, acting primarily by blocking peripheral 5-HT3 receptors in the intestinal nerves, as well as affecting central receptors in the vomiting center and the chemoreceptor trigger zone.
  2. BThe main antiemetic mechanism of action of these drugs is the blockade of dopaminergic receptors, which reduces esophageal and gastric motility.
  3. CAdverse reactions include euphoria, dysphoria, sedation, hallucinations, dry mouth, and increased appetite, and they may also cause autonomic effects such as tachycardia, conjunctival injection, and orthostatic hypotension.
  4. DThe oral bioavailability of ondansetron is 65%, and due to its prolonged half-life, it allows for single-dose administration.
Revelar gabarito e comentário

GabaritoA — They have a potent antiemetic effect, acting primarily by blocking peripheral 5-HT3 receptors in the intestinal nerves, as well as affecting central receptors in the vomiting center and the chemoreceptor trigger zone.

Link permanente: /questoes/qg223659